The advent of COVID-19 and the fast-tracked vaccine to prevent it has everyone talking. It is exciting when a vaccination can be developed, tested and produced at the pace at which the COVID-19 vaccine was generated. The world was waiting and the pharmaceutical industry answered. The question remains: what really is entailed in bringing a new vaccine to market and manufacturing enough supply for the whole world in a matter of months?
Professor Emadi’s course, Bio-Manufacturing: Pharmaceutical Processes, helps answer some of those questions and will serve as a foundational course in the engineering of these manufacturing processes for students who now may be considering the rapidly growing pharmaceutical manufacturing industry.
This compelling course, which is offered in Spring 2021, will give students a background in the fundamentals of biology and chemistry in engineering, allow them to examine case studies in pharmaceutical and vaccine manufacturing, and gain an understanding of key phrases in the process of drug manufacturing from bench to bottle.
Students will also learn the difference between conventional and biologics drugs, and gain an understanding of bioprocessing and bio-manufacturing as well as the main technologies used in the biopharmaceutical industry.
Students will gain:
- fundamentals of biology and chemistry in engineering
- examine case studies in pharmaceutical and vaccine manufacturing
- understand key phrases in the process of drug manufacturing from bench to bottle
- differentiate between conventional and biologics drugs
- understand bioprocessing and bio-manufacturing, and technologies used in the industry
Bio-Manufacturing: Pharmaceutical Processes, is listed under the course numbers MEM 3295 and BME 4985 and will be offered Tuesday/Thursday at 12:30-1:45 PM. Students who are interested in bio-manufacturing, pharmaceuticals, and those who want to gain more experience with biology and chemistry for engineering are encouraged to enroll.
Professor Emadi’s current focus is molecular, biochemical, and cell biology with an emphasis on the application and development of antibody phage display, protein engineering and cell-based assay. Her past work includes the bio production, the purification and the characterization of self-assembling peptide nanoparticles (SAPNs) as a novel immunogenic design of the Malaria and Influenza vaccine; the development of recombinant antibodies for the diagnosis and treatment of neurodegenerative diseases such as Alzheimer’s and Parkinson’s; the mechanisms of megakaryocytopoiesis dysregulation in myeloproliferative syndrome. She is an Assistant Professor in Residence with the Biomedical Engineering Department and also teaches with the Management and Engineering for Manufacturing (MEM) program.
Office: Engineering II, Room 312
Phone: (860) 881-0743
Frank J. Cunha, Ph.D., P.E.
Management for Engineering and Manufacturing, MEM,
Mechanical Engineering, ME, Departments
Ph. D., P.E., Mechanical Engineering, New York University.
Manufacturing Processes, Turbomachinery Design Development, Advanced Thermodynamics, Energy Systems, Solid Mechanics, Fracture Mechanics and Fatigue, Fluid Dynamics, Advanced Heat Transfer.
Professor-in-Residence, MEM and ME Departments 2019, United Technologies Pratt-Whitney Nov 1999 – March 2015 and April 1998 – Oct 1998 Development Leader for design of military and commercial aircraft engines, turbines, combustors and afterburners over 100 US patents, Siemens-Westinghouse Corporation Oct 1998 – Nov 1999 and March 1997 – April 1998 Principal Engineer development of land-based gas turbines 2 patents, General Electric Company January 1990 – Oct 1996 and June 1979 – Dec 1980 Edison and Staff Engineer responsible for the development of heavy-duty gas turbines 14 patents, Public Service Electric and Gas Company March 1981 – August 1989 Electrical Power Generation Staff Engineer.
Cunha, F.J., Gas Turbine Heat Transfer, Turbine Aerodynamics, Heat Transfer, Materials and Mechanics, Progress and Astronautics and Aeronautics, Vol. 243, ISBN-13: 978-1624102639.
Cunha, F.J., Turbine Heat Transfer Analysis, Gas Turbine Handbook, United States Department of Energy, National Energy Technology Laboratory.
Cunha, F.J., Trailing Edge Cooling for Gas Turbines, Special Section on Turbine Science and Technology, AIAA Journal of Propulsion and Power.
Cunha, F.J., Integrated High Performance Turbine Engine Technologies VII “Turbine Edge Cooling, United States Air Force, Air Force Material Command, Aeronautical Systems Center, Wright Patterson Air Force Research Laboratory.
Cunha, F.J., Enhanced Turbine Airfoil Lifing for Long Hot Missions, United States Air Force, Air Force Material Command, Aeronautical Systems Center, Wright Patterson Air Force Research Laboratory.
“Heat Transfer on Internal Surfaces of a Duct Subjected to Impingement of a Jet Array with Varying Jet Hole-Size and Spacing”, Journal of Turbomachinery, Vol.128.
“Effects of Coating Blockage and Deposit on Film-Cooling Effectiveness and Surface Heat Transfer”, AIAA 2006-0024.
Thermal-Mechanical Life Prediction System for Anisotropic Turbine Components Journal of Turbomachinery, TURBO-05-1110.
“Measured Adiabatic Effectiveness and Heat Transfer for Blowing from Tip of a Turbine Blade”, Journal of Turbomachinery, TURBO-04-1094, Vol. 125.
“Cooling the Tip of a Turbine Blade Using Pressure Side Holes – Part 1: Film Effectiveness”, Journal of Turbomachinery, TURBO-04-1095, Vol. 125.
“Cooling the Tip of a Turbine Blade Using Pressure Side Holes – Part 2: Heat Transfer Measurements”, Journal of Turbomachinery, TURBO-04-1096, Vol. 125.
“Comparison of Measurements and Predictions for Blowing from Turbine Blade Tip”, AIAA Journal of Propulsion and Power, Vol. 21.
“Adiabatic Effectiveness Measurements and Predictions of Leakage Flows on a Blade End-wall”, Journal of Turbomachinery, TURBO-04-1164.
“Inverse-BEM, Method to Determine Surface Temperatures at Inaccessible Surfaces” ASME.
Office: ITE 333
Phone: (860) 486-4462
About: Dr. Zhang received his BS and MS from Tsinghua University in China. He received his PhD from the University of Michigan.
Dr Zhang’s research interests are: modeling, analysis, continuous improvement, design, control, and energy efficient operations of manufacturing and service systems; Mathematical modeling and analysis of battery systems.
For more information about Dr. Zhang, please visit this page: https://www.ee.uconn.edu/faculty-staff-students/faculty/fac_liangzhang/
Office: UTEB 354
Phone: (860) 486-2855
Dr. Xu received his B.S. in Mechanical Engineering from Northeastern University, China (2008), M.S. in Mechanical Engineering from Tsinghua University, China (2010), and Ph.D. in Mechanical Engineering from Northwestern University, USA (2014). Prior to joining UConn, Dr. Xu was a research engineer in Ford Research and Advanced Engineering, Dearborn, Michigan (2014-2019).
Dr. Xu joined University of Connecticut in February 2019 as Assistant Professor in the Department of Mechanical Engineering. His research focuses on developing design optimization and uncertainty quantification methods for integrated manufacturing-material-structure design. His research interests also include Design for Additive Manufacturing (DfAM) and data mining-enhanced multi-disciplinary optimization of mechanical products.
For more information about Dr. Xu, please visit this page: https://hongyixu.lab.uconn.edu/
Office: Engineering II, room 315
Phone: (860) 486-0415
Dr. Van Scoter earned a BS and MS in Ceramic Engineering from the University of Washington – Seattle, an MS in Operations Research from the Colorado School of Mines, and a PhD in Industrial Engineering from Oregon State University.
Dr. Van Scoter is an Associate Professor in Mechanical Engineering. She served as the Co-Director of the Management and Engineering for Manufacturing (MEM) program for three years, completing her appointment in May 2016 and tripling student enrollment in the program.
Dr. Van Scoter has over twenty years of diverse industry experience, ranging from manufacturing at Boeing Commercial, work in quality and process improvement at an international logistics company and U.S. Department of Defense (DOD) in space optics, space survive-ability, and technology transfer. She has been both a technical and management consultant. Her work as a senior management consultant for Deloitte focused on improving operational and cost efficiency for U.S. and international companies and governments. As a senior technical consultant, she supported D.O.D. space optics and presented papers at International conferences on the dangers of space debris to spacecraft.
Her research field and applications include industrial engineering, process improvement, and studying the impact of contextual factors in STEM education. She has striven to injected real world examples and expectations into the junior and senior curriculum to better prepare students for employment requirements. Since arriving at the University of Connecticut in 2012, she was a champion of the MEM program, updating the program to reflect 21st century industry needs and standards, better serving UConn students, the university, employers, and the engineering profession.
Office: BUSN 384
Phone: (860) 486-2581
Dr. Thakur’s areas of expertise are: development and applications of linear, nonlinear, and integer programming methods in management science and function approximations in optimization mathematics.
For more information about Dr. Thakur, please visit this page: http://www.business.uconn.edu/contact/profiles/lakshman-thakur/
Office: UTEB 452
Phone: (860) 486-5911
Dr. Tang received his B.S. and M.S. in Applied Mechanics from Fudan University, China, in 1989 and 1992, and his Ph.D. in Mechanical Engineering from Penn State in 2001. From 1992 to 1995 he served as Lecturer at Fudan University in Applied Mechanics. Prior to joining UConn, Dr. Tang was a staff engineer at GE Corporate Research Center, Niskayuna, New York.
Dr. Tang joined the Mechanical Engineering Department in 2002. His current research interests are structural dynamics and system dynamics, active and passive structural controls, structural health monitoring/diagnosis, smart materials and mechatronics, and large-scale analysis of complex dynamic systems. His research projects are interdisciplinary, encompassing multi-physics modeling and analysis, electro-mechanical integration, and sensing/actuation development and signal processing. Dr. Tang’s research has been supported by federal agencies such as NSF and also by industries. While fundamental studies are being pursued in his lab to explore paradigm change in the structure and system dynamics area, research is also being carried out to implement the new findings to practical platforms such as aero-engines and fuel cells.
Dr. Tang was appointed as Co-Director of the Management and Engineering for Manufacturing (MEM) program in May 2016.
For more information about Dr. Tang, please visit this page: Structure and System Dynamics Research Laboratory
Office: Engineering II, room 313
Phone: (860) 486-0678
About: Dr. Roy earned her BS from Jadavpur University, India, MS from The Cooper Union, NY, and her Doctoral degree from Columbia University.
She has over 15 years of experiences working in reputed consulting firms such as Weidlinger Associates, BA&C, and WBCM in Massachusetts, New Jersey and Maryland. Her work involved analyzing, designing, and supervising construction of various types of existing and new buildings, bridges and other structures.
Office: BUSN 370
Phone: (860) 486-1333
Dr Nunez’ areas of expertise are convex optimization, combinatorial optimization, stochastic models, operations management and manufacturing, statistical modeling and simulation, computer programming and data structures, genetic algorithms, supply chain management, security and confidentiality in database systems, innovation and sustainability.
For more information about Dr. Nunez, please visit this page: http://www.business.uconn.edu/contact/profiles/manuel-nunez/
Office: BUSN 365
Phone: (860) 486-5914
About: Cuihong Li is an Associate Professor of Operations and Information Management at the School of Business, University of Connecticut. Her research explores operations and supply chain management, with a focus on the strategic interactions in the upstream and downstream supply chains, interfacing with economics, marketing, and information technology. Her current research studies problems in procurement and sourcing, supplier and consumer behavior, and service operations. Her research work has been published in Management Science, Manufacturing and Service Operations Management, Production and Operations Management, and other leading academic journals. She serves as a Senior Editor for Production and Operations Management, and an Associate Editor for Decision Support Systems. At UConn, she teaches core operations management and business decision modeling for the undergraduate, full-time MBA, and BAPM master programs. She received the Best Paper Award (2013) and Teaching Innovation Award (2015) of the School of Business. Cuihong earned her Ph.D. in Management of Manufacturing and Automation from the Tepper School of Business joint with the Robotics Institute, Carnegie Mellon University, and B.S. and M.S. degrees in Automation and Systems Engineering from Tsinghua University, China.
Dr. Li was appointed as Co-Director of the Management and Engineering for Manufacturing (MEM) program in 2019.
For more information about Dr. Li, please visit this page: http://www.business.uconn.edu/person/cuihong-li/